Malignancy – Introduction and Risk In Underlying Disease
Cancer is a term for a group of more than 100 diseases, in which cells divide uncontrollably, have the ability to invade and destroy surrounding tissues, and may spread to distant sites. Certain immune-mediated disease, including rheumatoid arthritis, psoriasis, Crohn’s disease, ulcerative colitis, and, to a lesser extent, ankylosing spondylitis and psoriatic arthritis have been associated with certain medical conditions including malignancy that significantly increase morbidity and mortality for patients. The potential relationship between these immune-mediated diseases and the risk of developing certain malignancies, including lymphomas, skin cancers, and other solid cancers are discussed in this topic of MEDVERSATION®. In addition, a general overview of cancer as a disease state, cancer screening and diagnosis, and various treatment options are discussed in Malignancy – Introduction.
Information presented in this section has been gathered from various sources, including retrospective and prospective randomized controlled clinical studies, cohort studies, published meta-analyses and registry data. This topic presents an overview of malignancy associated with immune-mediated inflammatory diseases. Information pertaining to the risk of malignancy with drug therapy is covered in a separate topic.
Content on this page was last reviewed on January 31, 2010.
Content on this page was last changed on January 12, 2010.
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